🔑 Key Insights Explanation:
1. Most human pathogens grow best at body temperature (mesophiles)
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Pathogens are harmful microbes that cause disease.
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Mesophiles are microbes that grow best at moderate temperatures, especially around 37°C (98.6°F) — which is human body temperature.
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So, many bacteria that infect humans are mesophiles because they survive and grow well inside the human body.
 
2. Most microbes that cause food spoilage are psychrotrophs
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Psychrotrophs are microbes that grow at cold to cool temperatures (like 4–20°C, fridge temperature).
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These microbes are the main cause of food spoilage in refrigerators.
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That’s why even refrigerated food can go bad after a while — because psychrotrophs can still grow slowly in the cold.
 
• There are rarer exceptions to these rules that can cause foodborne illness (think Listeria)
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Not all foodborne illness microbes are easy to predict.
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Listeria monocytogenes is an important exception — it can survive and grow in cold temperatures and cause illness even if food is refrigerated.
 
• Toxins: endotoxins in particular can be a problem even in cooked foods
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Endotoxins are toxins released from the cell wall of some bacteria (especially Gram-negative bacteria).
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The key point: even after cooking food and killing the bacteria, endotoxins can still remain and cause harm or illness.
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So food safety isn’t just about killing bacteria — it’s also about handling food properly before and after cooking.
 
3. Common microbial control measures in food include:
These are ways we can prevent or slow microbial growth in food:
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✅ Good hygiene – washing hands, utensils, surfaces.
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✅ Refrigeration – slows down microbial growth (especially psychrotrophs).
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✅ Curing – using salt, sugar, or adjusting pH to make food unfriendly for microbes.
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Example: salted meats, pickles (acidic), or sugary jams.
 
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📌 Summary:
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Mesophiles grow at body temp and cause human infections.
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Psychrotrophs grow in the fridge and cause food spoilage.
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Listeria is a rare bug that breaks the rules and grows in cold and causes illness.
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Endotoxins can survive cooking and still cause harm.
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Use hygiene, cold storage, and curing methods to keep food safe.
 
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